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The Chemical Constituents of Piper Methysticum / Or, The Chemical Constituents of the Active Principle of the Ava Root cover

The Chemical Constituents of Piper Methysticum / Or, The Chemical Constituents of the Active Principle of the Ava Root

By Alice A. Ball
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Drugs/Alcohol/PharmacologyScience - Chemistry/Biochemistry

About This Book

The thesis presents a systematic chemical investigation of the active principles of the ava root (Piper methysticum), beginning with historical uses and continuing through detailed laboratory methods for extraction and resin separation. It identifies distinct resin fractions and characterizes their metallic salts, oxidation products, and associated acidic components, and isolates neutral crystalline methysticin and related methysticinic acid. Analytical sections examine alcohol radicals and oxidative transformations, and a physiological chapter summarizes observed pharmacological effects. The conclusion synthesizes chemical findings and their relation to the root's narcotic and toxic properties.

About the Author

Ball, Alice A. portrait

Alice A. Ball

Alice A. Ball was an American chemist best known for her pioneering work in the field of medicinal chemistry. She is particularly recognized for developing the "Ball Method," which was the first effective treatment for leprosy using chaulmoogra oil. Her notable work, "The Chemical Constituents of Piper Methysticum / Or, The Chemical Constituents of the Active Principle of the Ava Root," reflects her contributions to understanding the chemical properties of natural substances. Ball's research laid the groundwork for future advancements in pharmacology and highlighted the importance of natural products in medicine.

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